Similarly, your serum osmolality will decrease when you drink too much water. The ADH plays a big role in bringing your serum osmolality back to its normal levels. Your body releases ADH when serum osmolality increases to keep water from leaving your system through the urine. It is quite obvious that the concentration of chemicals in your blood will increase when you don't drink enough water and continue to lose it through breathing, sweating and urinating. Antidiuretic hormone (ADH) is a substance that influences serum osmolality. Different chemicals can affect serum osmolality such as chloride, sodium, sugar and proteins. Serum osmolality is a test used to measure the amount of chemicals dissolved in the serum of the blood.
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